Status:

RECRUITING

Cognitive Remediation in Schizophrenia: Efficacy and Role of Neuroplasticity in "Top-down" and "Bottom-up" Mechanisms

Lead Sponsor:

University of Chile

Conditions:

Schizophrenia

Eligibility:

All Genders

18-59 years

Phase:

NA

Brief Summary

Schizophrenia patients have deficits of different degrees in several cognitive domains, impacting their social functioning and quality of life. Cognitive remediation strategies are useful to treat cog...

Detailed Description

Schizophrenia is a severe psychiatric illness that has a significant impact on patients, their families, and society. It presents with deficits of different degrees in all cognitive domains, including...

Eligibility Criteria

Inclusion

  • Diagnosis of schizophrenia according to Diagnostic and Statistical Manual (DSM)-5
  • Age between 18 and 59 years
  • Clinically stable outpatients
  • Current treatment with at least one antipsychotic medication

Exclusion

  • Significant medical or neurological comorbidity
  • Substance use disorder with illegal drugs in active use
  • Participation in a cognitive remediation program in the last 6 months

Key Trial Info

Start Date :

June 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 15 2026

Estimated Enrollment :

160 Patients enrolled

Trial Details

Trial ID

NCT06482918

Start Date

June 1 2024

End Date

March 15 2026

Last Update

July 1 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Clinica Psiquiatrica Universitaria, Hospital Clinico de la Universidad de Chile

Santiago, RM, Chile