Status:

NOT_YET_RECRUITING

Effectiveness of Exercise Plus Pain Neuroscience Education on Brain Function in Knee Osteoarthritis

Lead Sponsor:

Universidad Santo Tomas, Chile

Conditions:

Knee Osteoarthritis

Eligibility:

All Genders

45+ years

Phase:

NA

Brief Summary

A three-arm randomized controlled trial will be conducted. Fifty-nine participants with KOA will be recruited in a 1:1:1 ratio. Assessor, and statistician will be blinded to group allocation. One expe...

Eligibility Criteria

Inclusion

  • women and men at least 45 years old radiologically diagnosed with unilateral or bilateral KOA (Kellgren-Lawrence 1-3 grading scale)
  • pain duration greater than three months

Exclusion

  • Patients who have received physical therapy or other conservative therapy in the previous three months and those who have a history of major knee trauma and surgery in the last six months
  • cardiac pathology
  • structural use of psychoactive medications, such as antipsychotics, antidepressants, antiepileptics, and anxiolytics, during the past year
  • neurological diseases
  • other musculoskeletal clinical conditions that generate pain

Key Trial Info

Start Date :

March 15 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 30 2025

Estimated Enrollment :

57 Patients enrolled

Trial Details

Trial ID

NCT06482970

Start Date

March 15 2025

End Date

December 30 2025

Last Update

July 1 2024

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