Status:
COMPLETED
Efficacy of Fullerene in Preventing Radiation Dermatitis in Patients With Head and Neck Cancer .
Lead Sponsor:
West China Hospital
Conditions:
Radiation Dermatitis
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Radiotherapy always results in many complications such as radiation dermatitis, dry mouth, cranial nerve damage, and swallowing function. Among them, radiation dermatitis is confirmed to occur in the ...
Detailed Description
Radiotherapy (RT) is an important treatment for head and neck malignant tumors and can be used alone or in combination with chemotherapy as radical or adjuvant therapy. Complications such as radiation...
Eligibility Criteria
Inclusion
- Patients pathologically diagnosed with non-metastatic head and neck malignant tumors;
- Patients considered candidates for high-dose RT either as primary treatment or as postoperative treatment after surgical resection and patients planned to receive concomitant boost fractionation or concurrent systemic chemotherapy.
Exclusion
- Eastern Cooperative Oncology Group performance status of \>2;
- Pre-existing skin rash, ulceration or open wound in the treatment area;
- Known allergy to trolamine or fullerene;
- Inflammatory or connective tissue disorder of the skin;
- History of head and neck radiotherapy.
Key Trial Info
Start Date :
August 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2025
Estimated Enrollment :
132 Patients enrolled
Trial Details
Trial ID
NCT06484166
Start Date
August 1 2024
End Date
May 1 2025
Last Update
June 4 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
West China Hospital
Chengdu, Sichuan, China, 646000