Status:

COMPLETED

Goal Attainment Scaling (GAS) Sub-Study

Lead Sponsor:

LuMind IDSC Foundation

Collaborating Sponsors:

Ardea Outcomes Inc.

Pentara

Conditions:

Alzheimer's Disease in Down Syndrome

Eligibility:

All Genders

35+ years

Brief Summary

This is an optional sub-study that will enroll participants from LIFE-DSR parent protocol. The aim is to assess change over 16 months in individuals with Down syndrome through individualized goals set...

Detailed Description

People with Down syndrome are living longer. A longer life increases the chances of age-related risks of developing Alzheimer's disease and other forms of dementia. There is also growing evidence that...

Eligibility Criteria

Inclusion

  • The participant with DS and caregiver must be currently enrolled in the LIFE-DSR parent protocol.
  • The participant with DS must be age 35 years or older.
  • Both the participant with DS, or LAR, and their caregiver must be able to understand and be willing to sign written informed consent.
  • In the opinion of the Investigator, a participant's caregiver must have frequent interaction with the participant on a regular basis, agree to participate in clinic and remote visits, be able to provide accurate responses to questions about the participant with DS, and be capable of facilitating participation in the study visits.
  • Participant with DS and caregiver must be capable of reliably completing all study assessments at each time-point.
  • The caregiver must be able to converse in English.

Exclusion

  • Unable to complete trial procedures or adhere to the schedule of study assessments, in the opinion of the site PI.

Key Trial Info

Start Date :

June 30 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

February 29 2024

Estimated Enrollment :

46 Patients enrolled

Trial Details

Trial ID

NCT06484426

Start Date

June 30 2021

End Date

February 29 2024

Last Update

July 3 2024

Active Locations (5)

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Page 1 of 2 (5 locations)

1

University of California, San Diego

San Diego, California, United States, 920347

2

Advocate Health

Park Ridge, Illinois, United States, 60068

3

Kennedy Krieger Institute

Baltimore, Maryland, United States, 21205

4

Massachusetts General Hospital

Boston, Massachusetts, United States, 02129