Status:
NOT_YET_RECRUITING
Spatially Resolved IBD: Spatial Transcriptomics of Inflammatory Bowel Disease (IBD)
Lead Sponsor:
IRCCS San Raffaele
Collaborating Sponsors:
BGI, China
Conditions:
Patients With Histologically Confirmed CD Undergoing Intestinal Resection According to Standard of Care Due to Complicating Disease
Patients With Histologically Confirmed UC Undergoing Intestinal Resection According to Standard of Care Due to Complicating Disease
Eligibility:
All Genders
18-69 years
Brief Summary
The goal of this retrospective observational study is to obtain the spatial resolution of the entire intestinal fibrotic process through the technology STOmics Stereoseq. For this study we will use su...
Detailed Description
This is a monocentric observational study in which we will use the biological material from surgery carried out for normal clinical practice, and already stored at -80°C. This project has as purpose:...
Eligibility Criteria
Inclusion
- adult patient (age ≥18 years), both male and female patients with histologically confirmed CD and UC undergoing intestinal resection according to standard of care due to complicating disease, regardless of their current or past medical treatment;
- patients that have signed the IBD Biobank informed consent and consented to the use of their own biological material in future study or pertaining to the same field of investigation.
Exclusion
- \- patients with unconfirmed both UC and CD diagnoses;
- patients with superimposed dysplasia or cancer diagnosis and resections for which post- operative endoscopic assessment of recurrence is not feasible;
- patients who have not signed the IBD Biobank informed consent.
Key Trial Info
Start Date :
August 1 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 1 2025
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT06484738
Start Date
August 1 2024
End Date
August 1 2025
Last Update
July 3 2024
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
IRCCS Ospedale San Raffaele
Milan, Italy
2
Irccs Ospedale San Raffaele
Milan, Italy, 20132