Status:
COMPLETED
Mild Cognitive Impairment and Multidomain Intervention Package
Lead Sponsor:
University of Pittsburgh
Collaborating Sponsors:
Fogarty International Center of the National Institute of Health
Believers Church Medical College Hospital, Tiruvalla, Kerala, India
Conditions:
Dementia
Eligibility:
All Genders
50-65 years
Phase:
NA
Brief Summary
The state of Kerala, India has the highest proportion of older adults and the burden of lifestyle diseases causes great concern. Therefore, there is need for identifying a feasible multidomain prevent...
Detailed Description
In the context of increasing older adults, the burden of dementia is forecasted to increase in India. Interventions targeting risk factors and diseases may be the key element to counter the dementia e...
Eligibility Criteria
Inclusion
- Phase 1- All individuals (50-65yrs) consenting to participate will be included. Phase 3- Inclusion for multidomain intervention
- Individuals between 50-65 years old, willing to participate and comply with all the study evaluation and intervention procedures
- CAIDE (Cardiovascular Risk Factors, Aging and Dementia) Dementia Risk Score of 6 points or higher
- Those identified to have mild cognitive impairment in phase 1 screening
Exclusion
- • Phase 1- Those who are unable to respond, critically ill and having a physician diagnosed dementia report will be excluded.
- Phase 3- Exclusion for multidomain intervention
- Geriatric Depression Scale ≥ 9
- Dementia
- Disorders that may affect safe involvement in the intervention (eg, malignancy, symptomatic cardiovascular disease, Large vessel stroke in the past two years, History of transient ischemia attack (TIA) or small vessel stroke in the last 6 months, revascularization within 1 year previously, severe loss of vision, hearing, or communicative ability)
- Coincident participation in another intervention trial.
- Recent (\< 3 months) bone fracture.
- History of hip fracture, joint replacement, or spinal surgery in the last 6 months
- Clinically significant abnormalities in laboratory blood tests as per judgment of the site study clinician.
Key Trial Info
Start Date :
June 15 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 30 2025
Estimated Enrollment :
481 Patients enrolled
Trial Details
Trial ID
NCT06488430
Start Date
June 15 2024
End Date
September 30 2025
Last Update
December 2 2025
Active Locations (1)
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1
Believers Church Medical College
Tiruvalla, Kerala, India, 689 103