Status:

NOT_YET_RECRUITING

PROgram to Enhance Cardiovascular Risk Trough an Intervention of Nutrition in Bipolar Disorder

Lead Sponsor:

University of Sao Paulo

Collaborating Sponsors:

Deakin University

Conditions:

Bipolar Depression

Bipolar Disorder (BD)

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

Individuals with Bipolar Disorder (BD) have twice the risk of being affected by metabolic comorbidities and a 1.8-fold increased risk of mortality from cardiovascular diseases when compared to the gen...

Eligibility Criteria

Inclusion

  • Clinical diagnosis of Bipolar disorder types I and II diagnosis
  • Adults of both genders, from 18 to 60 years old
  • In typical pharmacotherapy for BD, for at least one month
  • Agreement to participate in the study with signature of the consent form

Exclusion

  • Patients with "very good or excellent" diet quality assessed by the diet quality scale (ESQUADA): \>275 out of a score of 375
  • Patients in a state of hypomania or mania: score \>8 (Young Mania Rating Scale - YMRS)
  • Patients with severe depression \>21 Montgomery-Åsberg Depression Rating Scale
  • Patients at low cardiovascular risk (\<7 points for men or \<9 points for women on the Framingham Global Risk Score)
  • Low weight or eutrophic body mass index: \<25kg/m² as in similar studies
  • Pregnant or breastfeeding women
  • Patients diagnosed with anorexia and bulimia nervosa
  • Patientes diagnosed with Irritable Bowl Syndrome or other diagnosed conditions that affect the gastrointestinal function

Key Trial Info

Start Date :

February 1 2026

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2026

Estimated Enrollment :

74 Patients enrolled

Trial Details

Trial ID

NCT06488573

Start Date

February 1 2026

End Date

December 1 2026

Last Update

March 17 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Fernanda Gabriel

São Paulo, São Paulo, Brazil, 04514102

PROgram to Enhance Cardiovascular Risk Trough an Intervention of Nutrition in Bipolar Disorder | DecenTrialz