Status:
RECRUITING
Fecal Amino Acids，Gut Taste Receptors and Irritable Bowel Syndromes
Lead Sponsor:
Second Affiliated Hospital of Xi'an Jiaotong University
Conditions:
Irritable Bowel Syndrome
Eligibility:
All Genders
18-80 years
Brief Summary
Clinical data, fresh feces and intestinal mucosal tissues of patients with diarrheal IBS were collected. High performance liquid chromatography, immunohistochemistry and immunofluorescence were used t...
Eligibility Criteria
Inclusion
- Patients with IBS who meet the Rome IV diagnostic criteria:
- that is, recurrent abdominal pain, with symptoms occurring at least 1 day per week or at least 3 days per month on average in the last 3 months, combining 2 or more of the following:
- related to defecation;
- accompanied by changes in the frequency of bowel movements;
- Accompanied by changes in fecal characteristics (appearance). (Symptoms appeared at least 6 months before diagnosis, and above diagnostic criteria were met in the last 3 months) 2. Age ≥18 years old.
Exclusion
- 1\. History of celiac disease and other organic intestinal diseases, metabolic diseases (thyroid dysfunction, diabetes, etc.); (2) Serious neurological, mental and psychological diseases, or accompanied by serious organ dysfunction; 3. Abdominal surgery; 4. Pregnant, possible pregnant and lactating patients; 5. History of colonoscopy in the past 1 year; 6. Declined to participate in the study.
Key Trial Info
Start Date :
March 16 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 1 2024
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06489444
Start Date
March 16 2023
End Date
August 1 2024
Last Update
July 8 2024
Active Locations (1)
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1
The second affiliated hospital of xi'an jiaotong university
Xi'an, Shaanxi, China, 710004