Status:
ENROLLING_BY_INVITATION
Neural Computations of Goal-directed Decision-making
Lead Sponsor:
Cedars-Sinai Medical Center
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
California Institute of Technology
Conditions:
Epilepsy Intractable
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The purpose of this research is to better understand how the human brain accomplishes the cognitive task of making goal-directed decisions. These investigations are critical to better understand human...
Detailed Description
Flexible goal-directed decision-making is a core aspect of higher-order adaptive biological intelligence. A number of psychiatric disorders involve impairments in goal-directed decision-making, yet th...
Eligibility Criteria
Inclusion
- Intractable epilepsy, undergoing invasive monitoring
- Age ≥13
- Full Scale Intelligence Quotient \> 70
- Ability to comprehend and perform simple behavioral tasks by pressing buttons on laptop computer in response to questions
Exclusion
- Determination by clinicians and investigators that a patient is unable to complete the behavioral tasks required for the protocol due to either cognitive limits, psychological limits, or pain
Key Trial Info
Start Date :
August 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2028
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT06489561
Start Date
August 1 2023
End Date
July 1 2028
Last Update
July 18 2025
Active Locations (1)
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1
Cedars-Sinai Medical Center
Los Angeles, California, United States, 90048