Status:
RECRUITING
Menopause Transition, Sex Hormone Deficiency and Autonomic and Vascular Function
Lead Sponsor:
University of Minnesota
Conditions:
Menopause
Eligibility:
FEMALE
45-55 years
Brief Summary
This is a longitudinal study to determine the influence of the menopause transition on autonomic and vascular function. PI Keller-Ross has published data demonstrating that postmenopausal females have...
Eligibility Criteria
Inclusion
- Female
- age 45-55 years
- premenopausal
- not using any medications determined to affect autonomic function
- eumenorrheic
- not planning to become pregnant for the duration of participation in the study
- English-speaking, literate, willing and able to provide informed consent.
Exclusion
- Diabetes
- pregnant or breastfeeding
- cardiac or pulmonary disorders
- severe obesity (body mass index \[BMI\] ≥ 40 kg/m 2 )
- hypertension
- obstructive sleep apnea
- current use of heart or blood pressure medications, current use of hormonal contraceptives or other forms of exogenous sex hormones
- report of nicotine/tobacco use in the last six months, report of current alcohol abuse,
- history of treatment with chemotherapy/radiation
- coagulopathy disorders and/or use of anticoagulant medications, and current use of anxiolytics and/or antidepressants.
Key Trial Info
Start Date :
April 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 21 2030
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT06490146
Start Date
April 1 2025
End Date
August 21 2030
Last Update
May 8 2025
Active Locations (1)
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1
University of Minnesota
Minneapolis, Minnesota, United States, 55414