Status:
NOT_YET_RECRUITING
Multiparameter Optimized tES for Memory in Aging
Lead Sponsor:
Medical University of South Carolina
Conditions:
Healthy Aging
Eligibility:
All Genders
50-85 years
Phase:
NA
Brief Summary
With an aging population worldwide, it is critical to develop effective interventions promoting healthy cognitive aging. Transcranial electrical stimulation (tES) is a promising but not fully realized...
Detailed Description
With an aging population worldwide, it is critical to develop effective interventions promoting healthy cognitive aging. A key component of healthy cognition is intact working memory, an executive neu...
Eligibility Criteria
Inclusion
- 50 - 85 y.o.
- Endorse good health with no history of mental or physical illness
- Willingness to adhere to the study schedule and assessments
- Able to read consent document and provide informed consent.
- English is a first or primary fluent language.
Exclusion
- Any current psychiatric diagnosis or current Clinical Global Impression ratings of psychiatric illness \> 1
- Neurodevelopmental disorders, history of Central Nervous System (CNS) disease, concussion, overnight hospitalization, or other neurologic sequela, tumors, seizures, meningitis, encephalitis, or abnormal CT or MRI of the brain
- Any psychotropic medication is taken within 5 half-lives of procedure time
- Any head trauma resulting in loss of consciousness
- Visual impairment (except the use of glasses)
- Inability to complete cognitive testing
- Active participation or plan for enrollment in another evidence-based clinical trial affecting the psychosocial function
- Repeated abuse or dependence upon drugs (excluding nicotine and caffeine) or taking medications including stimulants, modafinil, thyroid medication, or steroids
- Implanted devices/ferrous metal of any kind
- History of seizure or epilepsy, currently taking medications that lower seizure thresholds
- Claustrophobia or other conditions that would prevent the MRI assessment.
- Pregnancy (or suspected/possible pregnancy or plan to become pregnant in the short term).
- Urine Pregnancy Test: If the subject is a woman of childbearing potential and /or a man capable of fathering a child before, during, and/or after participation precautions should be taken. Examples of acceptable methods of birth control for participants involved in the study include birth control pills, patches, Intrauterine Devices (IUD), condoms, sponges, diaphragm with spermicide, or avoiding sexual activity that could cause the subject to become pregnant.
- Inability to adhere to the treatment schedule.
- Inability to fit the wearable device to the user's head.
Key Trial Info
Start Date :
December 31 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT06491264
Start Date
December 31 2025
End Date
December 31 2026
Last Update
June 12 2025
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