Status:

RECRUITING

Clinical Outcomes and Inflammatory Responses in Viral vs. Bacterial Sepsis

Lead Sponsor:

Sichuan Provincial People's Hospital

Conditions:

Sepsis

Sepsis Bacterial

Eligibility:

All Genders

18-90 years

Brief Summary

This observational cohort study aims to compare clinical outcomes and inflammatory responses between patients with viral sepsis, specifically COVID-19-associated sepsis, and those with bacterial sepsi...

Detailed Description

Sepsis, a major cause of morbidity and mortality in ICU patients, has garnered increased attention during the COVID-19 pandemic due to the high mortality rates associated with viral sepsis. This study...

Eligibility Criteria

Inclusion

  • Patients diagnosed with sepsis according to Sepsis 3.0 criteria.
  • Patients with confirmed bacterial sepsis based on positive bacterial cultures.
  • Patients with confirmed viral sepsis, specifically COVID-19, diagnosed via RT-PCR for SARS-CoV-2 for viral group and negative for bacterial group.
  • Patients aged 18 years and older.
  • Patients admitted to the ICU during the study period.

Exclusion

  • Patients with mixed bacterial and viral infections.
  • Patients with sepsis not meeting the Sepsis 3.0 criteria.
  • Patients who received immunomodulatory therapies other than standard treatments (e.g., investigational drugs).
  • Pregnant or breastfeeding women.

Key Trial Info

Start Date :

April 2 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

July 10 2024

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT06491966

Start Date

April 2 2024

End Date

July 10 2024

Last Update

July 9 2024

Active Locations (1)

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Sichuan Provincial People's Hospital

Chengdu, Sichuan, China, 610091