Status:
RECRUITING
Assessing Optimal Inhaler Strategies During Acute Exacerbations of COPD (AECOPDs) Using Oscillometry
Lead Sponsor:
McGill University Health Centre/Research Institute of the McGill University Health Centre
Collaborating Sponsors:
MEI/MES I&P Program (McGill University, Thorasys Inc.)
Conditions:
COPD
COPD Exacerbation Acute
Eligibility:
All Genders
40+ years
Brief Summary
Chronic Obstructive Pulmonary Disease (COPD) is a persistent lung disease that makes it very difficult to breathe. The airways and the normally 'spongy' lungs themselves are affected. The main treatme...
Detailed Description
Three sets of carefully timed oscillometry and dyspnea score measurements will be performed: 1) at "baseline", before the participant receives their scheduled dose of LABD and roughly 4 hours followin...
Eligibility Criteria
Inclusion
- Males and females, age ≥ 40, who are former/current smokers with a ≥10 pack-year smoking history.
- COPD previously confirmed by spirometry (FEV1/FVC \< 0.7) of any severity (GOLD 1-4).
- Currently experiencing and receiving treatment for a physician-diagnosed AECOPD with both long-acting and short-acting bronchodilators prescribed by their treating team.
- Ability to participate without supplemental oxygen during the oscillometry tests.
- Ability to provide informed consent.
Exclusion
- No COPD diagnosis.
- AECOPD is not the principal cause of urgent care visit, emergency department visit, or hospitalization.
- Treatment strategy in which LABDs were held by the treating medical team (SABD-only approach).
- Participant already performed spirometry on the same day of testing.
- Inability to provide informed consent.
Key Trial Info
Start Date :
July 19 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
43 Patients enrolled
Trial Details
Trial ID
NCT06495047
Start Date
July 19 2024
End Date
December 31 2025
Last Update
July 23 2024
Active Locations (1)
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1
McGill University Health Centre
Montreal, Quebec, Canada, H4A 3J1