Status:
COMPLETED
Arterial Pressure Derived Dynamic Parameters to Detect Preload Responsiveness in Mechanically Ventilated Patients Under Spontaneous Mode
Lead Sponsor:
CHU de Reims
Conditions:
General Critically Ill Patients With Hypovolemia
Eligibility:
All Genders
18+ years
Brief Summary
The management of septic shock patients includes the infusion of fluids, however fluids may be deleterious if the patient does not respond by increasing cardiac output. By consequence, it is now recom...
Detailed Description
\*Objectives: Primary : to assess the diagnostic performance of the decrease in Pulse Pressure Variation (PPV) during a Passive Leg Raising test (PLR) to predict preload responsiveness in mechanicall...
Eligibility Criteria
Inclusion
- Patient over 18 years old.
- Hospitalized in intensive care.
- For which the clinician in charge of the patient will need to predict the response to fluids and decide on a possible infusion of fluids, because of:
- Acute circulatory failure with mean arterial pressure \< 65mmHg or \< 30mmHg of its baseline value for hypertensive patients.
- And/or other signs of hemodynamic instability (tachycardia, mottling, oliguria, hyperlactatemia).
- In mechanically ventilated patients under spontaneous mode.
- Previously equipped with an arterial catheter.
- Affiliated to a social security scheme.
Exclusion
- Patient with arrythmia (PPV is not applicable).
- Patient with intra-abdominal hypertension (PLR test is not valid).
- Patient with a contraindication/impossibility to the PLR maneuver (lower limb amputation, respiratory intolerance).
- Patient with poor echogenicity noted previously.
- Patient protected by law.
Key Trial Info
Start Date :
January 29 2024
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 27 2025
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT06495489
Start Date
January 29 2024
End Date
March 27 2025
Last Update
July 9 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Chu Reims
Reims, France, 51092