Status:

ACTIVE_NOT_RECRUITING

Open Trial of Technology-Enhanced Behavioral Intervention for Buprenorphine Retention in Pregnant and Postpartum People

Lead Sponsor:

Medical University of South Carolina

Collaborating Sponsors:

National Institute on Drug Abuse (NIDA)

Conditions:

Opioid Use Disorder

Pregnancy Related

Eligibility:

FEMALE

18-45 years

Phase:

EARLY_PHASE1

Brief Summary

This study involves testing how useful a technology-enhanced intervention is for pregnant people prescribed buprenorphine for the management of opioid use disorder. The intervention being studied is a...

Detailed Description

Medication for opioid use disorder (MOUD) can effectively prevent overdose and death for pregnant and postpartum people with opioid use disorder (OUD). Yet, only half of birthing people continue to us...

Eligibility Criteria

Inclusion

  • Currently pregnant and less than 33 weeks gestational age,
  • History of OUD within past 3 years,
  • Confirmed prescription for sublingual buprenorphine products (i.e., Suboxone, Subutex, Zubsolv) for the purpose of treating OUD,
  • Living in the United States,
  • Between 18-45 years of age.

Exclusion

  • Carrying multiples (i.e., twins, triplets, etc.);
  • High-risk pregnancies including the following conditions: hyperemesis defined as hospitalization for intractable nausea and vomiting, hypertensive disorders of pregnancy (e.g., gestational hypertension, preeclampsia), placenta previa, or vaginal bleeding in current pregnancy after the first trimester;
  • Current psychotic symptoms and/or active suicidal intent;
  • Experiencing cognitive or emotional impairment that precludes providing informed consent;
  • Incarcerated/pending incarceration or institutionalized during the study period.

Key Trial Info

Start Date :

August 6 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 31 2026

Estimated Enrollment :

26 Patients enrolled

Trial Details

Trial ID

NCT06496230

Start Date

August 6 2024

End Date

January 31 2026

Last Update

July 11 2025

Active Locations (1)

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1

Medical University of South Carolina

Charleston, South Carolina, United States, 29403