Status:
RECRUITING
miRNA in Septic Acute Kidney Injury
Lead Sponsor:
University Hospital Ostrava
Collaborating Sponsors:
University Hospital Olomouc
Conditions:
Sepsis
Acute Kidney Injury
Eligibility:
All Genders
18-100 years
Brief Summary
Acute kidney injury is a common and serious complication of sepsis and septic shock, which may be associated with a worse outcome of the patient's condition. The exact pathophysiological mechanism of ...
Detailed Description
Sepsis is generally characterized as a life-threatening organ dysfunction and dysregulating host reaction to the infection (e.g., bacterial, viral, mycotic (1). Typical pathophysiological processes of...
Eligibility Criteria
Inclusion
- The study group of patients with sepsis with or without acute kidney injury
- age \> 18 years
- newly diagnosed sepsis or septic shock with or without acute kidney injury
- Healthy volunteers
- no evidence of infection on clinical or laboratory examination
- age \> 18 years
- signed informed consent
Exclusion
- The study group of patients with sepsis with or without acute kidney injury
- age \< 18 years
- chronic kidney disease at stage 4 or 5 according to KDIGO recommendations (KDIGO) for chronic kidney disease 2024
- patients on chronic dialysis treatment, or after renal transplantation
- Healthy volunteers
- acute or chronic infection
- renal disease
Key Trial Info
Start Date :
May 2 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2027
Estimated Enrollment :
220 Patients enrolled
Trial Details
Trial ID
NCT06498336
Start Date
May 2 2024
End Date
December 31 2027
Last Update
July 12 2024
Active Locations (2)
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1
University Hospital Ostrava
Ostrava, Moravian-Silesian Region, Czechia, 708 52
2
University Hospital Olomouc
Olomouc, Olomouc Region, Czechia, 779 00