Status:
NOT_YET_RECRUITING
Role of Transcranial Doppler and Magnetic Resonance Angiography for Future Management of Sickle Cell Anemia CNS.
Lead Sponsor:
Eman Abdul-Hai
Conditions:
Blood Disease
Brain Injuries
Eligibility:
All Genders
2-18 years
Brief Summary
This study aimed to determine the Predictive Value of Transcranial Doppler and Magnetic Resonance Angiography for Future Management of Sickle Cell Anemia. Specific aims are: Demonstrate silent paren...
Detailed Description
Cerebro-vascular accident is a destructive complication of sickle cell disease, CVA is a important cause of morbidity and mortality individuals with SCD, which cause motor and neurocognitive complicat...
Eligibility Criteria
Inclusion
- (1) age, from 24 months to 18 years; (2) hemoglobinopathy diagnosis of Hb SS; (3) the desire and ability to be screened as evidenced by signed parental informed consent and child's assent; (4) the availability for follow-up for at least 2 years.
Exclusion
- \- 1.Other sickle cell syndromes were excluded because they had a lower or uncertain risk of stroke.
- A child was excluded from TCD screening for any of the following: an indication for chronic blood transfusion or a contraindication to chronic transfusion, participation in any study involving treatments which might confound the interpretation of the results of the proposed work
Key Trial Info
Start Date :
September 1 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2025
Estimated Enrollment :
18 Patients enrolled
Trial Details
Trial ID
NCT06498726
Start Date
September 1 2024
End Date
October 1 2025
Last Update
July 12 2024
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