Status:

RECRUITING

Comparing the Impact of Four Types of Meditation Practices for Relaxation in Cancer Survivors

Lead Sponsor:

City of Hope Medical Center

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Hematopoietic and Lymphatic System Neoplasm

Malignant Solid Neoplasm

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This clinical trial compares the impact of four types of meditation practices, breathing only, focused attention only, mindfulness only, and breathing, focused attention and mindfulness combined, for ...

Detailed Description

PRIMARY OBJECTIVE: I. Assess the feasibility to attend and complete the meditation program as scheduled (combined arms) within six weeks. EXPLORATORY OBJECTIVES: I. Assess the ability of breathing,...

Eligibility Criteria

Inclusion

  • Documented written informed consent of the participant
  • Age: ≥ 18 years
  • Ability to understand and fluently speak English or Spanish
  • No previous training in mind-body relaxation techniques including meditation, yoga, tai chi, qigong, guided imagery, mindfulness-based stress reduction, hypnosis, or cognitive behavior therapy, that exceeds 3 hours. Additionally, no regular practice of mind-body relaxation techniques, or formal experience with mind-body relaxation techniques within the past 12 months
  • Visual Analog Scale (VAS) anxiety score of \> 3 from a range from 0 to 10. A "0" means the lowest anxiety score and a "10" means the highest anxiety score
  • Long-term cancer survivors who received surgery to treat their cancer ( \> 6 months since last treatment) with no history of chemotherapy, radiation therapy, or other systemic therapy (e.g., hormonal therapy) and/or have completely recovered from surgery OR patients identified as having pre-cancerous lesions that have been surgically treated (e.g., colon polyp that has been removed)
  • Willingness to:
  • Provide salivary alpha-amylase sample
  • Complete stress tests and study questionnaires
  • Be monitored with a Bispectral Index (BIS) device

Exclusion

  • Inability to complete study required time and procedures as outlined in the study procedures section of the protocol
  • Must not have had previous serious illnesses that affect neurological functioning such as strokes, heart attacks, Parkinson disease, etc
  • Ongoing active psychiatric condition, depressive/bi-polar related disorders, anxiety, psychosis disorders, or substance use that may interfere with the study including panic disorder, major depression, schizophrenia, and bipolar disease
  • Active cancer
  • Cancer survivors who have received chemotherapy, radiation therapy, or any other systemic treatment (e.g., hormonal therapy)
  • Women who are pregnant

Key Trial Info

Start Date :

June 17 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 17 2026

Estimated Enrollment :

44 Patients enrolled

Trial Details

Trial ID

NCT06500377

Start Date

June 17 2024

End Date

June 17 2026

Last Update

July 11 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

City of Hope Medical Center

Duarte, California, United States, 91010

2

City of Hope at Irvine Lennar

Irvine, California, United States, 92618