Status:
RECRUITING
Biomarkers in Autoimmune Disease of Nervous System
Lead Sponsor:
Tongji Hospital
Conditions:
Autoimmune Diseases of the Nervous System
Neuromyelitis Optica Spectrum Disorder
Eligibility:
All Genders
18+ years
Brief Summary
Neurological autoimmune diseases are a group of disorders characterized by the abnormal immune response attacking the nervous system, including the brain, spinal cord and peripheral nerves. These dise...
Detailed Description
Autoimmune diseases of the nervous system are a type of disease in which the human immune system mistakenly attacks its own nervous system, causing damage to the structure and function of the nervous ...
Eligibility Criteria
Inclusion
- Clinical diagnosis with autoinflammatory diseases of the nervous system, including: Neuromyelitis Optica Spectrum Disorder (NMOSD), Myasthenia Gravis (MG), Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP), idiopathic inflammatory myopathy(IIM), multiple sclerosis (MS), autoimmune encephalitis (AE), Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD), ect al.
- sex and age-matched healthy individuals
Exclusion
- Known history of primary immunodeficiency (innate or acquired).
- Patients with severe central nervous system, pulmonary, or other systemic infections.
- Patients with secondary central nervous system demyelinating lesions, such as those caused by vasculitis, systemic lupus erythematosus, and Sjögren's syndrome.
- Patients with vascular (including hemorrhagic and ischemic), hereditary metabolic, neoplastic, or toxic diseases.
- Pregnant or lactating women.
Key Trial Info
Start Date :
July 31 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2027
Estimated Enrollment :
50000 Patients enrolled
Trial Details
Trial ID
NCT06502015
Start Date
July 31 2024
End Date
July 1 2027
Last Update
November 20 2024
Active Locations (1)
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1
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, China, 430030