Status:

RECRUITING

Non-ablative Diode Laser Therapy for Genitourinary Syndrome of Menopause: A Prospective Study on Efficacy, Safety, and Quality of Life and Sexuality Impact

Lead Sponsor:

University of Cagliari

Conditions:

Genitourinary Syndrome of Menopause

Eligibility:

FEMALE

45-73 years

Brief Summary

The goal of this observational study is to evaluate the efficacy, safety, and impact on quality of life and sexuality of non-ablative dual-wavelength diode laser treatments in managing Genitourinary S...

Eligibility Criteria

Inclusion

  • Post-menopausal women aged 45-73 years.
  • Sexually active.
  • Experiencing physiological amenorrhea for more than 12 months.
  • Exhibiting at least one symptom of Genitourinary Syndrome of Menopause (GSM).
  • Not using lubricants or hormonal therapy in the previous 6 months.
  • Able to provide written informed consent.

Exclusion

  • Untreated uterine or vulvovaginal cancers.
  • Pacemaker or other implanted electrode carriers.
  • Severe multi-organ or neurological diseases.
  • Active sexually transmitted infections.
  • Moderate to severe uterine prolapse.
  • Active urinary tract infections.
  • Acute or chronic dermatological conditions in the vulvar or vaginal area.
  • Active genital herpes.
  • Active high-risk Human Papillomavirus (HPV).
  • Ischemic tissues, unhealed wounds, sores, or undiagnosed mucosal or epithelial alterations.
  • Recent unhealed invasive or ablative surgeries.
  • Bleeding disorders or anticoagulant therapy.
  • Immunodeficiencies.
  • Uncontrolled diabetes.

Key Trial Info

Start Date :

September 1 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 1 2025

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT06503003

Start Date

September 1 2023

End Date

January 1 2025

Last Update

July 16 2024

Active Locations (1)

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Division of Gynecology and Obstetrics Department of Surgical Sciences, University of Cagliari, Cagliari, Italy

Cagliari, CA, Italy, 09042