Status:
NOT_YET_RECRUITING
Impact of Uterine Immune Profiling and Personalized Treatments in Patients Receiving a Single Blastocyst: a Matched Controlled Study
Lead Sponsor:
Matricelab Innove
Conditions:
Infertility
Success Rate of Assisted Reproductive Therapy
Eligibility:
FEMALE
18-41 years
Brief Summary
A recent randomised controlled trial and previous large cohort studies have shown that the uterine immune environment is a crucial element in improving the performance of Assisted Reproductive therapy...
Detailed Description
The PRECONCEPTIO software will be used to extract all the uterine immune profiles carried out between January 2020 and June 2023 for patients attending the two reproductive centres, Bluets and Diaconn...
Eligibility Criteria
Inclusion
- For case: Uterine immune profiling followed by a Day-5 fresh SET or day-5 or Day-6 freeze-thawed SET within the nine months following the uterine immune profiling between January 2020 and June 2023.
- Will be excluded patients with no SET day-5, with uterine immune profiling more than nine months before, or with no matching pair For control: Blastocyst SET without uterine immune profiling within the year prior the embryo transfer matched to the case group between January 2018 on June 2023
- maternal age (+/-1 year) and
- the past history of ART (same number of previous oocytes pick-up, same number of previous embryo transfer) and
- the same type of transfer (IVF, ICSI, frozen transfer) and
- the same category of expansion of the blastocoel (B1-B2/ B3-B4/ B5-B6).
Exclusion
Key Trial Info
Start Date :
January 15 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 30 2025
Estimated Enrollment :
340 Patients enrolled
Trial Details
Trial ID
NCT06503952
Start Date
January 15 2025
End Date
May 30 2025
Last Update
December 27 2024
Active Locations (2)
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1
Hopital des Bluets- centre d'assistance medicale à la procreation
Paris, Ile de, France, 75012
2
Hopital des diaconnesse- Centre d'assistance medicale a la procreation
Paris, Île-de-France Region, France, 75012