Status:
RECRUITING
Ovarian Tissue Cryopreservation and Subsequent Auto-Transplantation for Female Cancer Patients (HKCH)
Lead Sponsor:
Chinese University of Hong Kong
Conditions:
Neoplasms
Eligibility:
FEMALE
12-18 years
Phase:
NA
Brief Summary
Ovarian tissue freezing is an ideal option for these patients as it can be performed immediately and does not need any time for ovarian stimulation. We hope we can develop this service in our locality...
Detailed Description
To date, transplantation of cryopreserved ovarian tissue has resulted in births of at least 130 children but data on transplantation of ovarian tissue removed before puberty are scarce. During ovaria...
Eligibility Criteria
Inclusion
- Patients aged from 0-35 years old and diagnosed with cancer e.g., leukaemia, myeloproliferative or myelodysplastic diseases, lymphoma, bone tumours, neurological neoplasms and sarcoma, Paediatric bone marrow transplant patients
- Patients with any illness or who will undergo any type of treatment that may cause irreversible damage to their fertility, such as extensive abdominal surgery, high toxicity medication and treatments;
- Patients suffering from hormone-sensitive malignancies who will undergo medical treatment, such as radiotherapy and chemotherapy that is liable to damage their ovaries and deter them from conception in the future.
Exclusion
- Patients with no anticipated oncologic therapies Patients who are pregnant Children with one ovary Children deemed high risk for perioperative complications Patients unable to provide consent/assent (i.e. significant psychiatric problems/cognitive delay)
- \-
Key Trial Info
Start Date :
August 13 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 31 2041
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06505057
Start Date
August 13 2024
End Date
July 31 2041
Last Update
January 8 2026
Active Locations (1)
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1
Hong Kong Children's Hospital
Hong Kong, Hong Kong