Status:

ENROLLING_BY_INVITATION

Addressing COVID-19 Vaccine Hesitancy With Muliti-Level Interventions in Appalachia

Lead Sponsor:

Marc Kiviniemi

Collaborating Sponsors:

National Institute on Minority Health and Health Disparities (NIMHD)

Conditions:

COVID-19

Vaccine Hesitancy

Eligibility:

All Genders

18-99 years

Phase:

NA

Brief Summary

The purpose of this community-engaged study is to test the ability of county-level strategies to increase uptake of COVID-19 vaccination. In this study the key objective is to test whether health comm...

Detailed Description

The intervention trial will be a community-based, three-arm cluster randomized controlled trial. The three arms are: (1) multilevel invention (vaccine communication campaign + community-level structur...

Eligibility Criteria

Inclusion

  • Up to 2,250 participants will take part in the study --- approximately 150 residents in each of the 15 participating Appalachian Kentucky Counties. In each of the fifteen counties, the investigators will collect survey data from 150 adults who are served by Homeplace, a medical and social services organization run by the UK Center for Excellence in Rural Health, which provides services in each of the 15 partner counties. Homeplace provides services to adults who are medically underserved and typically at 100-133% of the federal poverty level, primarily through service delivery by trained local Community Health Workers (CHWs). CHWs will recruit participants and collect the survey data from the identified individuals. Importantly, the criteria for qualification for Homeplace services are equivalent across the 15 counties, providing equivalence of sample across counties. A random sample of 150 individuals per county will be drawn from the Homeplace client database for that county. Gender, ethnic background, and health status will roughly mirror that of the demographics of the county.
  • Must be a current Homeplace client
  • Live in one of the 15 selected study counties
  • Over the age of 18
  • Have the ability to complete the survey in English

Exclusion

  • Not a current Homeplace client
  • Primary residence is not in one of the 15 study counties
  • Not within the ages of 18-99 years old
  • English is not your primary language

Key Trial Info

Start Date :

September 1 2026

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2027

Estimated Enrollment :

2250 Patients enrolled

Trial Details

Trial ID

NCT06505993

Start Date

September 1 2026

End Date

September 1 2027

Last Update

September 19 2025

Active Locations (1)

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1

University of Kentucky Center of Excellence in Rural Health

Hazard, Kentucky, United States, 41701