Status:

RECRUITING

Nausea Induced by Radiation of the Dorsal Vagal Complex for Benign Brain Tumors (NausiCAA)

Lead Sponsor:

University Hospital, Bordeaux

Conditions:

Benign Brain Tumor

Eligibility:

All Genders

18+ years

Brief Summary

Patients irradiated to the brain frequently experience nausea. The dorsal vagal complex (DVC) area is a specific brainstem zone and has been identified as likely responsible for nausea. Existing clini...

Detailed Description

Patients irradiated to the brain frequently experience nausea. The dorsal vagal complex (DVC) area is a specific brainstem zone and has been identified as likely responsible for nausea. Existing clini...

Eligibility Criteria

Inclusion

  • More than 18 years old
  • With benign brain tumor
  • Irradiated with conventional fractionation (1,8-2Gy/fraction)

Exclusion

  • History of brain radiation
  • History of head and neck radiation
  • Demencia
  • Concurrent chemotherapy
  • Nausea at the time of inclusion
  • Anti-nausea treatment : corticosteroids, metoclopramide, setrons, other

Key Trial Info

Start Date :

May 20 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 1 2026

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT06506578

Start Date

May 20 2022

End Date

June 1 2026

Last Update

July 30 2025

Active Locations (3)

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Page 1 of 1 (3 locations)

1

CHU de Bordeaux, Service de Radiothérapie

Bordeaux, France

2

Hospices Civils de Lyon, Service d'Oncologie Radiothérapie - Hôpital Neurologique

Lyon, France

3

Institut de cancérologie Strasbourg Europe (ICANS), Service d'Oncologie Radiothérapie

Strasbourg, France