Status:

NOT_YET_RECRUITING

Introduction of Dispersible 3HP Formulations for TB Preventive Treatment in Children: a Multi-country Evaluation

Lead Sponsor:

The Aurum Institute NPC

Collaborating Sponsors:

Johns Hopkins University

KNCV Tuberculosis Foundation

Conditions:

TB - Tuberculosis

Household Contact

Eligibility:

All Genders

Brief Summary

The WHO has recommended TB preventive therapy (TPT) for children living with HIV (CLHIV) and household contacts of people living with TB, however, the scale-up and implementation of TPT has been sub-o...

Eligibility Criteria

Inclusion

  • Clinic record review
  • Medical records of children \<12 years who are either CLHIV or who are household contacts of people with pulmonary TB and who are initiated on TPT

Exclusion

  • Records will be excluded for children who are contacts of a drug-resistant, have presumptive TB disease or are currently on TB treatment
  • Qualitative study
  • Inclusion Criteria:
  • Adult caregiver (\>18 years) of a child \<12 years of age who is eligible for TPT
  • Healthcare worker from one of the clinics in which the study will be conducted who sees outpatient pediatric consultations including TB-exposed children
  • Policy maker or program manager who manages or is involved in PMTCT, TB and/or pediatric programming

Key Trial Info

Start Date :

August 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 1 2025

Estimated Enrollment :

1200 Patients enrolled

Trial Details

Trial ID

NCT06511180

Start Date

August 1 2024

End Date

June 1 2025

Last Update

July 19 2024

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Introduction of Dispersible 3HP Formulations for TB Preventive Treatment in Children: a Multi-country Evaluation | DecenTrialz