Status:
RECRUITING
Acupressure in Patients With Sickle Cell Disease
Lead Sponsor:
Indiana University
Collaborating Sponsors:
University of California, Irvine
Conditions:
Sickle Cell Disease
Eligibility:
All Genders
14-80 years
Phase:
NA
Brief Summary
The proposed research is to determine the clinical efficacy and neurobiological mechanisms of acupressure analgesia in patients with sickle cell disease (SCD).
Detailed Description
This study will help the investigators learn whether acupressure, a non-pharmacological alternative treatment approach, can help manage pain in patients with sickle cell disease. Acupressure involves ...
Eligibility Criteria
Inclusion
- Any gender
- 14-17 (Adolescents) and 18-80 (Adults) years old
- Have been diagnosed with SCD and experiencing chronic pain in the past 6 months or vaso-occlusive crisis/crises in the past 12 months.
- Either outpatient or inpatient or status changing between each other
- Willing to limit the current and the introduction of any new medications or treatment modalities for control of pain symptoms during the study visits.
- Willing to stick to the scheduled acupressure treatments every other day for 5 weeks.
- Fluent in English and capable of giving written informed consent.
Exclusion
- Recent/ongoing alternative pain management with acupuncture/acupressure or acupuncture/acupressure-related techniques within the last 6 months.
- Presence of a concurrent autoimmune or inflammatory disease such as rheumatoid arthritis, systemic lupus erythematosus, inflammatory bowel disease, etc. that causes pain or any other chronic pain condition with pain greater than sickle pain.
- Diseases/conditions history includes but not limited to:
- Head injury with substantial loss of consciousness
- Known non-SCD-related severe psychiatric illnesses (e.g. current schizophrenia, major depression with suicidal ideation).
- Significant visual, motor, or auditory impairment that would interfere with ability to perform study visits-related activities
Key Trial Info
Start Date :
March 7 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2029
Estimated Enrollment :
240 Patients enrolled
Trial Details
Trial ID
NCT06511453
Start Date
March 7 2024
End Date
August 1 2029
Last Update
December 10 2024
Active Locations (2)
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1
University of California, Irvine
Irvine, California, United States, 92868
2
Indiana University School of Medicine
Indianapolis, Indiana, United States, 46075