Status:

COMPLETED

Clinical Validation of mμSORS for Non-invasive Blood Glucose Detection in Non-diabetic Subjects

Lead Sponsor:

Shanghai Jiao Tong University School of Medicine

Collaborating Sponsors:

Shanghai Photonic View Technology Co., Ltd.

Conditions:

Diabetes Mellitus

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This is a single-center, open-label, prospective study. Blood glucose is measured at different time points during oral glucose tolerance test and hypoglucose clamp test in healthy subjects, using both...

Detailed Description

In order to clinically verify the accuracy and safety of non-invasive blood glucose measurement by the mμSORS technology specifically in the 3-10 mmol/l glucose range, this study will conduct oral glu...

Eligibility Criteria

Inclusion

  • Inclusion Criteria :
  • Male or female.
  • Aged\>=18 years for OGTT participants or aged between 20 and 40 years for hypoglucose clamp tests participants.
  • Fasting blood glucose (FPG) \< 6.1 mmol/L and glycated hemoglobin (HbA1c) \< 5.7% during the screening period.
  • There are no scars, obvious pigmentation and other factors that interfere with the detection of the palm skin to be tested.
  • Confirmed as healthy based on the results of physical examination, medical history, vital signs and clinical laboratory tests.
  • Fully understand the nature, significance, possible benefits, possible inconveniences or potential risks of this research, and should also understand the research procedures, be willing to complete the entire research process, and provide written consent form.
  • Exclusion Criteria :
  • With diabetes history.
  • Any history of serious clinical diseases such as circulatory system, endocrine system, nervous system, digestive system, respiratory system, hematology, immunology, psychiatry or metabolic abnormality, or any other disease that can interfere with the test results, which the investigator considers significant.
  • Alcohol dependency or drug abuse.
  • Those who have participated in clinical trials of other drugs within 3 months before screening (since the last visit of the previous trial).
  • Those who have used any drugs that affect blood glucose levels (such as insulin, oral hypoglycemic drugs, steroid hormones, thyroxine, etc.) within 28 days before screening;
  • Pregnancy or lactation period.
  • Difficulty in venous blood collection or fainting of needles or blood.
  • Other circumstances that the investigator considers inappropriate to participate in the study.

Exclusion

    Key Trial Info

    Start Date :

    July 11 2024

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    September 15 2024

    Estimated Enrollment :

    30 Patients enrolled

    Trial Details

    Trial ID

    NCT06512077

    Start Date

    July 11 2024

    End Date

    September 15 2024

    Last Update

    January 28 2025

    Active Locations (1)

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    Page 1 of 1 (1 locations)

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    Ruijin Hospital

    Shanghai, Shanghai Municipality, China, 200025