Status:

NOT_YET_RECRUITING

Plasticizer Exposure and Its Consequences on Health

Lead Sponsor:

Medical University of Vienna

Collaborating Sponsors:

University of Vienna

Conditions:

Beta-thalassemia

Glioma

Eligibility:

All Genders

18+ years

Brief Summary

Plasticizers are chemicals commonly found in many everyday items, from food packaging to medical equipment. Although they are pervasive in our daily lives, researchers still don't have a clear picture...

Detailed Description

Wider research context: Industrial plasticizers are ubiquitous in modern society, utilized in products ranging from food packaging to medical supplies. Despite their widespread use, the health implica...

Eligibility Criteria

Inclusion

  • TDTM:
  • Inclusion: Adult, homozygous ß-Thalassemia Major, transfusion dependency.
  • Exclusion: Plastic implants, chronic infectious disease, pregnancy.
  • Thalassemia Intermedia/Minor:
  • Inclusion: Adult, homozygous/heterozygous ß-Thalassemia Intermedia/Minor
  • Exclusion: Plastic implants, chronic infectious disease, pregnancy, transfusion dependency
  • Healthy adults:
  • Inclusion: Adult
  • Exclusion: Chronic disease, plastic implants, infectious disease, pregnancy, anemia, medication-, drug-, or alcohol-abuse
  • Glioma patients:
  • Inclusion: Adult, high/low-grade glioma, tumor larger then 3cm, resection with access to the ventricular system
  • Exclusion: Large intraventricular hemorrhage, plastic implants, infectious disease
  • ICU patients:
  • Inclusion: Adult, brain hemorrhage, external CSF drain from ventricle
  • Exclusion: intraventricular hemorrhage, plastic implants, ECMO, hemodialysis, infectious disease
  • Patients undergoing diagnostic lumbar-puncture:
  • Inclusion: Adult, diagnostic CSF sampling, outpatient setting
  • Exclusion: Ventricular hemorrhage, plastic implants, infectious disease

Exclusion

    Key Trial Info

    Start Date :

    October 1 2024

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    September 30 2027

    Estimated Enrollment :

    120 Patients enrolled

    Trial Details

    Trial ID

    NCT06512298

    Start Date

    October 1 2024

    End Date

    September 30 2027

    Last Update

    July 24 2024

    Active Locations (1)

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    1

    Medical University of Vienna

    Vienna, Austria, 1090

    Plasticizer Exposure and Its Consequences on Health | DecenTrialz