Status:

RECRUITING

Study on the Correlation Between Fat Soluble Vitamins and Non-alcoholic Fatty Liver Disease

Lead Sponsor:

First Affiliated Hospital of Zhejiang University

Conditions:

Non-Alcoholic Fatty Liver Disease

Fat Soluble Vitamin Deficiencies and Disorders

Eligibility:

All Genders

18+ years

Brief Summary

Excessive or insufficient levels of vitamins in the body can affect health. With the prevalence of obesity and MetS, NAFLD has become the leading cause of chronic liver disease and abnormal liver bioc...

Detailed Description

This is a single center cross-sectional study. In this study, 4000 eligible patients will be recruited and demographic information and clinical data of all study subjects will be collected. According ...

Eligibility Criteria

Inclusion

  • Age ≥ 18 years old, both male and female;
  • Voluntarily participate in this study and sign an informed consent form;
  • Diagnosed NAFLD through abdominal ultrasound;

Exclusion

  • Acute and chronic infections, severe cardiovascular and cerebrovascular diseases, respiratory system diseases, urinary system diseases, rheumatic diseases, tumors, and pituitary dysfunction; Or have hepatitis B, hepatitis C virus, or acquired immunodeficiency syndrome;
  • Surgery was performed within 6 months, and blood donation, transfusion, or significant blood loss occurred within 4 months;
  • Have taken vitamin supplements within 2 weeks;
  • Women are in pregnancy, lactation, or within one year after childbirth;
  • Alcohol abuse (alcohol intake ≥ 140 g/week for males and ≥ 70 g/week for females)
  • The serum creatinine (SCr) exceeds twice the following abnormal values, with the standard of abnormal values being: male (20-59 years old)\>97 μ mol/L, male (60-79 years old)\>111 μ mol/L; Female (20-59 years old)\>73 μ mol/L, female (60-79 years old)\>81 μ mol/L.

Key Trial Info

Start Date :

July 3 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

July 10 2026

Estimated Enrollment :

4000 Patients enrolled

Trial Details

Trial ID

NCT06512701

Start Date

July 3 2024

End Date

July 10 2026

Last Update

July 22 2024

Active Locations (1)

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First Affiliated Hospital of Zhejiang University

Hangzhou, Zhejiang, China, 310003

Study on the Correlation Between Fat Soluble Vitamins and Non-alcoholic Fatty Liver Disease | DecenTrialz