Status:

RECRUITING

A Pragmatic Randomized Controlled Trial to Predict Postpartum Hemorrhage

Lead Sponsor:

Holly Ende

Collaborating Sponsors:

Vanderbilt University Medical Center

Conditions:

Post Partum Hemorrhage

Eligibility:

FEMALE

Phase:

NA

Brief Summary

This research project aims to enhance the safety of childbirth by using advanced computer models to predict the risk of postpartum hemorrhage (PPH). PPH is a significant concern for mothers during an...

Detailed Description

Postpartum hemorrhage (PPH) is a common complication following vaginal or cesarean delivery and contributes significantly to maternal morbidity and mortality in the United States. There are numerous c...

Eligibility Criteria

Inclusion

  • All vaginal and cesarean deliveries occurring at Vanderbilt University Medical Center

Exclusion

  • All patients will be randomized at the time of admission to the obstetric service. Patients who are discharged prior to delivery will be excluded from subsequent analysis. Any patients with a pre-delivery planned hysterectomy (for placenta increta or percreta) will be excluded from the treatment algorithm and primary analysis.

Key Trial Info

Start Date :

January 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2027

Estimated Enrollment :

10000 Patients enrolled

Trial Details

Trial ID

NCT06513351

Start Date

January 1 2025

End Date

July 1 2027

Last Update

October 1 2025

Active Locations (1)

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1

Vanderbilt University Medical Center

Nashville, Tennessee, United States, 37212