Status:
WITHDRAWN
Investigating Changes in Responses to Controlled Effective Doses of Ozone at Different Exercise Intensities
Lead Sponsor:
Michael Koehle
Collaborating Sponsors:
Natural Sciences and Engineering Research Council, Canada
Conditions:
Ozone
Exercise Intensity
Eligibility:
All Genders
18-50 years
Phase:
NA
Brief Summary
The project will look to investigate whether exercise during ozone exposure performed for a shorter duration at a higher intensity is more harmful than exercise performed for a longer duration at a li...
Detailed Description
Purpose and Hypothesis The purpose of the study is to investigate whether exercise performed at a higher intensity for a shorter duration during ozone exposure results in greater decrements in pulmona...
Eligibility Criteria
Inclusion
- Currently training and/or competing in endurance sport
- Maximal oxygen consumption (VO2max) greater than 60 ml/kg/min (males) or 50 ml/kg/min (females)
- Between the ages of 18 and 50
- Able to communicate sufficiently using the English language
- Taking hormonal birth control (female participants only)
Exclusion
- History of smoking
- Upper respiratory tract infection within the last 4 weeks
- EIB, Asthma
- Presence of any chronic respiratory disease
- Current symptoms of, or current infection with COVID-19
- Pregnant or suspected pregnancy
Key Trial Info
Start Date :
September 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2025
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT06513754
Start Date
September 1 2024
End Date
August 1 2025
Last Update
March 30 2025
Active Locations (1)
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1
Environmental Physiology Laboratory
Vancouver, British Columbia, Canada, V6T 1Z1