Status:

RECRUITING

The Effects of Different Ventilation Modes on Patients With Pulmonary Lobe Resection

Lead Sponsor:

Mao Enting

Conditions:

Lung Injury

Lung Inflammation

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

The objective of this study was to discuss the effects of different ventilation modes on patients with plasma inflammatory factor and respiratory function in patients with pulmonary removal.

Detailed Description

Patients who meet the inclusion criteria will be numbered in the order of admission, and a dedicated person will prepare codes and opaque envelopes for random allocation. This study was divided into 3...

Eligibility Criteria

Inclusion

  • Comprehensive examination and analysis of imaging, laboratory examination and other comprehensive examinations, the diagnosis is clear, which is in line with lobe resection surgical indications
  • Age 18-75 years old, the gender is not limited;
  • ASA grading Ⅰ \~ III level;
  • It is expected that the single lung ventilation time is ≥1 hours, and ≤3 hours

Exclusion

  • Emergency surgery;
  • There is a taboos on the existence of systemic anesthesia;
  • There is a history of acute chronic upper respiratory infections in the past January;
  • Previous bronchial asthma, chronic obstructive pulmonary disease, bronchial dilatation, phthisis ,aspergillosis , acute respiratory distress syndrome or history of respiratory failure;
  • Merge the function of important organs such as heart, liver, and kidney;
  • There was a history of chest surgery and the history of trauma;
  • Preoperative lung function test obvious abnormal abnormal abnormalities (1 second of exhalation (FEV1) \<60%);
  • Patients refuse to participate in the clinical trial

Key Trial Info

Start Date :

January 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 1 2025

Estimated Enrollment :

102 Patients enrolled

Trial Details

Trial ID

NCT06514729

Start Date

January 1 2024

End Date

May 1 2025

Last Update

July 23 2024

Active Locations (1)

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1

Affiliated Hospital of Zunyi Medical University

Zunyi, Guizhou, China, 563000