Status:

NOT_YET_RECRUITING

Effects of Anesthesia Technique on Endothelial Function

Lead Sponsor:

Bagcilar Training and Research Hospital

Conditions:

Endothelial Dysfunction

Ischemia Reperfusion

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

The aim of this study was to compare the effects of two different anesthesia methods, general anesthesia and infraclavicular block, on oxidative stress and endothelial dysfunction in upper extremity f...

Detailed Description

Pneumatic tourniquets are commonly used in orthopedic extremity surgeries to reduce surgical trauma and blood loss. When the tourniquet is released, it leads to the release of more free oxygen radical...

Eligibility Criteria

Inclusion

  • Scheduled for upper extremity surgery using a pneumatic tourniquet
  • American Society of Anesthesiologists (ASA) physical status classification I

Exclusion

  • Under 18 or over 65 years of age
  • Hypertension
  • Diabetes mellitus
  • Malignancy
  • Cardiovascular disease history (congestive heart failure, myocardial infarction, venous thrombosis)
  • Cerebrovascular disease history
  • Liver/kidney dysfunction
  • Pregnant or breastfeeding women
  • History of substance and tobacco use
  • History of extremity ischemia

Key Trial Info

Start Date :

August 25 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 30 2025

Estimated Enrollment :

106 Patients enrolled

Trial Details

Trial ID

NCT06515028

Start Date

August 25 2024

End Date

January 30 2025

Last Update

August 13 2024

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