Status:
COMPLETED
Transcranial Direct Current Stimulation (tDCS) in Young Individuals with Major Depressive Disorder: a Literature Review and Feasibility Study
Lead Sponsor:
The University of Hong Kong
Conditions:
Major Depressive Disorder
Eligibility:
All Genders
16-25 years
Phase:
NA
Brief Summary
Objectives: (1) To assess the therapeutic effects of tDCS on improving depressive symptoms in young individuals with Major Depressive Disorder (MDD), relative to sham stimulation ; and (2) to evaluate...
Detailed Description
The incidence of probable depression during the fifth peak of COVID-19 was 24.6%, within the HK population, with the youths having experienced a disproportionately higher rate. A recent epidemiology s...
Eligibility Criteria
Inclusion
- Diagnosed with major depressive disorder (MDD) according to the Structured Clinical Interview for DSM-5, Clinical Version (SCID-DSM-5, CV)
- Scored ≥ 14 (i.e., at least mild to moderate depression on the 17-item Hamilton Depression Rating Scale (HDRS) at screening and at baseline;
- Right handedness;
- Stable dosage of antidepressants or other treatments for depression in recent 4 weeks; and
- Can read and write Chinese.
Exclusion
- History of significant head trauma, neurological disorders (e.g., epilepsy), seizures;
- First degree relative with epilepsy;
- Concomitant unstable medical conditions; major neurological conditions;
- Comorbid disorders listed in the DSM-V, e.g., schizophrenia, substance use disorder, mental retardation, etc.;
- Pregnancy, lactating women, or women planning pregnancy;
- Device or metal clips on or inside the skull, cardiac pacemaker;
- Inability to provide informed consent.
Key Trial Info
Start Date :
July 31 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 31 2024
Estimated Enrollment :
8 Patients enrolled
Trial Details
Trial ID
NCT06518642
Start Date
July 31 2024
End Date
October 31 2024
Last Update
November 27 2024
Active Locations (1)
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1
University of Hong Kong
Hong Kong, Hong Kong