Status:
COMPLETED
Tryptophan Requirements During Pregnancy
Lead Sponsor:
University of British Columbia
Collaborating Sponsors:
Canadian Institutes of Health Research (CIHR)
Conditions:
Pregnancy
Eligibility:
FEMALE
20-40 years
Phase:
NA
Brief Summary
Pregnancy is an important period of life where there is an increased need for nutrients including protein and amino acids from food. The current protein and amino acids dietary recommendations were al...
Detailed Description
Pre-Study: All participants will arrive following a 10-12 hrs overnight fasting, to allow the anthropometric measurements, biochemical, and dietary assessments. Fasting blood glucose by finger prick ...
Eligibility Criteria
Inclusion
- Cis-gendered pregnant woman.
- 20-40 years of age.
- Pregnant with a single child.
- Between 11-20 weeks of gestation or 31-40 weeks of gestation.
- Free of chronic diseases/acute diseases and have a full range of physical mobility.
Exclusion
- Women who are not pregnant.
- Women who are pregnant with more than one child (this changes amino acid demands) or were pregnant in the 6 months before the current pregnancy.
- Women with a history of spontaneous abortion (within the last 6 months) or preterm birth.
- Women not in good health or have a metabolic, cardiovascular, neurological, genetic, or immune disorder, including gestational diabetes, preeclampsia, pregnancy-related anemia, or pregnancy-related jaundice.
- Claustrophobic women (a clear hood will be placed, which can easily be removed, over the participants head for approximately 20 min to measure energy expenditure).
- Women who are substance dependent (i.e., alcohol, tobacco, illicit drugs).
- Women who have severe nausea/vomiting throughout their pregnancy.
- Women under the age of 20 years and over the age of 40 years.
- Women who have lost weight (approximately 1.5kg or more) during their current pregnancy.
- Women with a pre-pregnancy Body Mass Index (BMI) under 19 or over 28 〖kg/m〗\^2.
Key Trial Info
Start Date :
July 20 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 18 2025
Estimated Enrollment :
29 Patients enrolled
Trial Details
Trial ID
NCT06519071
Start Date
July 20 2023
End Date
July 18 2025
Last Update
September 16 2025
Active Locations (1)
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1
BC Children's Hospital Research Institute, University of British Columbia
Vancouver, British Columbia, Canada, V5Z4H4