Status:
RECRUITING
Improving Independent Multi-joint Arm Control After Stroke
Lead Sponsor:
University of Houston
Collaborating Sponsors:
UT Health Houston
Korea Advanced Institute of Science and Technology
Conditions:
Stroke
Eligibility:
All Genders
40-75 years
Phase:
NA
Brief Summary
The purposes of this study include: 1. \- To identify whether features of aberrant intermuscular coordination patterns can be used to predict motor impairment after stroke. 2. \- To test whether musc...
Detailed Description
Stroke is a leading cause of long-term disability in the United States. Of the more than 700,000 Americans who experience a stroke each year, two-thirds survive. 69% of patients who were admitted to a...
Eligibility Criteria
Inclusion
- Inclusion criteria for aged matched healthy group
- Male or female whose age range between 40 and 75
- no known neurological injuries
- Exclusion criteria for aged matched healthy group
- have an orthopedic disorder involving upper limbs;
- have a history of any neurologic disease;
- have any history of epilepsy of the potential participants and/or their family members;
- are unable to consent;
- are pregnant.
- Inclusion criteria for stroke group
- male or female hemiparetic chronic stroke survivors;
- age ranging between 40-75 year;
- with single unilateral ischemic or hemorrhagic middle cerebral artery stroke;
- neurologically stable for \>6 months;
- have an expectation that current medication will be maintained without changes for at least 3 months. Stable use of anti-spasticity medication (e.g., baclofen, diazepam, tizanidine) is accepted;
- without severe spasticity (Modified Ashworth (MA) \<4);
- have not received botulinum toxin on the impaired arm within 3 months.
- Exclusion criteria for stroke group
- have an orthopedic disorder involving upper limbs;
- cognitive impairment sufficient to interfere with informed consent or successful completion of the protocol (Montreal Cognitive Assessment (MoCA) score \< 26);
- a history of another neurologic disease;
- anesthesia of joint position sense in upper limbs;
- are pregnant or have a chance that they might be (self-reported);
Exclusion
Key Trial Info
Start Date :
September 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2029
Estimated Enrollment :
74 Patients enrolled
Trial Details
Trial ID
NCT06523335
Start Date
September 1 2024
End Date
September 1 2029
Last Update
July 26 2024
Active Locations (1)
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1
University of Houston
Houston, Texas, United States, 77204