Status:
RECRUITING
Trabeculopuncture as Predictive Test for the Success of Ab Interno Trabeculectomy
Lead Sponsor:
Wuerzburg University Hospital
Conditions:
Open Angle Glaucoma
Pseudoexfoliation Glaucoma
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to perform trabeculopuncture a test to determine the distal outflow tract function to predict the success of ab interno trabeculectomy.
Detailed Description
The aim of this study is to develop a non-invasive predictive test for the function of the distal outflow tract after ab interno trabeculectomy for open angle glaucoma. We hypothesize that the ocular ...
Eligibility Criteria
Inclusion
- individuals ≥ 18 years of age
- clinical diagnosis of: primary open angle glaucoma, pigmentary glaucoma, or pseudoexfoliation glaucoma
- uncontrolled intraocular pressure (IOP) with maximally tolerated medical therapy
- progressive thinning of retinal nerve fiber layer assessed by Spectral domain optical coherence tomography (p \< 0.05)
- progression of visual field defects
- visually significant cataract and indication to reduce IOP or glaucoma medication burden
Exclusion
- clinical diagnosis of neovascular glaucoma, angle-closure glaucoma, uveitic glaucoma, neovascular glaucoma
- prior glaucoma surgery
- preexisting conditions affecting the episcleral venous pressure including Grave's ophthalmopathy, Sturge-Weber syndrome, Arteriovenous fistulas (carotid-cavernous fistula)
Key Trial Info
Start Date :
June 13 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 31 2026
Estimated Enrollment :
55 Patients enrolled
Trial Details
Trial ID
NCT06523751
Start Date
June 13 2023
End Date
January 31 2026
Last Update
April 3 2025
Active Locations (1)
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1
Uniklinikum Würzburg
Würzburg, Bavaria, Germany, 97080