Status:

RECRUITING

Choline and Iron Deficiency

Lead Sponsor:

University of Minnesota

Conditions:

Pediatric Iron Deficiency

Anemia

Eligibility:

All Genders

5-7 years

Phase:

PHASE2

PHASE3

Brief Summary

BACKGROUND: Iron deficiency limits the neurodevelopmental potential of more than 200 million children each year. Iron therapy is typically started when iron deficiency anemia is first diagnosed after...

Eligibility Criteria

Inclusion

  • Age 6 months +/- 28 days
  • Hb \< 11.0 g/dL
  • ZPP \> = 80
  • T\<37.5°C
  • Malaria-negative based on Rapid Diagnostic Test (RDT)
  • Mother is HIV-negative.

Exclusion

  • Developmental disorder
  • Severe malnutrition (severe wasting or bipedal edema)
  • Known sickle cell disease
  • Neurologic disorder, brain injury, or other condition affecting brain development
  • Not currently breastfeeding
  • Birthweight \< 2000 g

Key Trial Info

Start Date :

August 11 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 21 2027

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT06527391

Start Date

August 11 2025

End Date

September 21 2027

Last Update

August 27 2025

Active Locations (1)

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1

University of Minnesota

Minneapolis, Minnesota, United States, 555455