Status:

NOT_YET_RECRUITING

Blood Biomarkers Based Screening for HPV-driven OPC

Lead Sponsor:

UNICANCER

Conditions:

Head and Neck Squamous Cell Carcinoma

Anal Cancer

Eligibility:

MALE

50+ years

Phase:

NA

Brief Summary

The objective of our study is to demonstrate that it is possible to detect and treat human papilloma virus (HPV)-related oropharyngeal cancers (OPC) early using simple blood tests. The success of this...

Detailed Description

OPC caused by HPV are the most common head and neck cancers and are expected to increase in the future, especially since HPV vaccines are not widely used. Currently, there are no screening strategy av...

Eligibility Criteria

Inclusion

  • Aged ≥50 years from the general population
  • Man
  • No previous history of HPV-driven cancer or head neck cancer
  • Willingness to complete follow up visits

Exclusion

  • Aged \< 50 years
  • Woman
  • History of HPV-driven cancer or head and neck cancer
  • Psychiatric conditions
  • Inability to complete follow up visits
  • Severe medical condition (life expectancy \<5 years)
  • Previous prophylactic HPV vaccination

Key Trial Info

Start Date :

January 1 2026

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 1 2032

Estimated Enrollment :

10000 Patients enrolled

Trial Details

Trial ID

NCT06528353

Start Date

January 1 2026

End Date

January 1 2032

Last Update

September 19 2025

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