Status:
NOT_YET_RECRUITING
Impact of Smoking on Salivary Interleukin (IL)-39, IL-41, IL-1β, TNF-α Levels in Periodontal Disease
Lead Sponsor:
Necmettin Erbakan University
Conditions:
Periodontitis, Adult
Smoking
Eligibility:
All Genders
18-65 years
Brief Summary
The goal of this observational study is to evaluate if the measurement of salivary Interleukin (IL)-39, IL-41, IL-1Beta(β), and Tumor necrosis factor-alpha (TNF-α) levels can aid in the early diagnosi...
Eligibility Criteria
Inclusion
- The periodontitis groups (Non-smoking and smoking) in the study will include systemically healthy patients who are clinically diagnosed with Stage II and III, generalized, Grade B, C periodontitis based on the consensus report of the 2017 World Workshop on Classification of Periodontal and Peri-Implant Diseases and Conditions.
- Agreeing to participate in the study
Exclusion
- use of oral contraceptive drugs
- use of antibiotics, immunosuppressants, or drug therapies in the last 6 months before the study;
- history of excessive alcohol use;
- pregnancy or breastfeeding status;
- periodontal treatment during the last 6 months before the study.
- Not agreeing to participate in the study
- Not meeting the inclusion criteria
Key Trial Info
Start Date :
August 1 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 15 2024
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06528522
Start Date
August 1 2024
End Date
September 15 2024
Last Update
July 30 2024
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