Status:

RECRUITING

Malaria Molecular Surveillance in Mozambique (Phase 2)

Lead Sponsor:

Centro de Investigacao em Saude de Manhica

Collaborating Sponsors:

Barcelona Institute for Global Health

University of California, San Francisco

Conditions:

Malaria

Falciparum Malaria

Eligibility:

All Genders

6+ years

Brief Summary

Mozambique is among the ten countries with the highest burden of malaria worldwide, with an estimated 10.3 million cases in 2021. Malaria transmission is highly heterogeneous across the country, with ...

Detailed Description

The AIM of this project is to strengthen and scale Molecular Malaria Surveillance (MMS) in Mozambique for quality, timely, and appropriate optimization of the public health benefits of the NMCP 2023-2...

Eligibility Criteria

Inclusion

  • A) CHILDREN AT HEALTH FACILITIES
  • Informed, written consent to participate from the guardian
  • Children 2-10 years of age
  • Fever (axillary temperature ≥37.5ºC) or history of fever in the preceding 24 hours
  • At least one positive parasitological test for malaria diagnosis via RDT (HRP2 or LDH)

Exclusion

  • Unwilling to provide informed, written consent
  • Age \<2 years or \>10 years
  • not resident in study area
  • Any symptoms of severe malaria
  • Negative of both (HRP2 and LDH) parasitological test for malaria via RDT
  • History of antimalarial treatment in the last 14 days
  • B) PREGNANT WOMEN AT ANC
  • Inclusion Criteria:
  • Pregnant women attending first antenatal care visit
  • Resident in the study area
  • Pregnant Women older than 12 years old
  • Informed, written consent to participate from participant and/or guardian

Key Trial Info

Start Date :

April 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

March 31 2027

Estimated Enrollment :

18750 Patients enrolled

Trial Details

Trial ID

NCT06529237

Start Date

April 1 2024

End Date

March 31 2027

Last Update

August 26 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Centro de Investigaçao em Saúde de Manhiça

Manhiça, Maputo Province, Mozambique, 1929