Status:
RECRUITING
Microclots and Neutrophil Activation as Potential Indicators for Stroke Risk and Reperfusion Failure
Lead Sponsor:
University of Zurich
Collaborating Sponsors:
Empa, Swiss Federal Laboratories for Materials Science and Technology
Conditions:
Ischemic Stroke
Eligibility:
All Genders
18+ years
Brief Summary
Stroke remains a major health burden worldwide. Many patients are severely disabled and stay in need of care. Mechanical thrombectomy has dramatically improved outcomes for stroke patients with large ...
Detailed Description
Background: Stroke remains a major health burden worldwide. Many patients are severely disabled and stay in need of care. Since introducing mechanical thrombectomy as a therapeutic option, clinical o...
Eligibility Criteria
Inclusion
- Patients without acute stroke CS or CSG
- No previous stroke or previous stroke ≥ 1 year ago
- Signed informed consent
- Patients with acute stroke (AS-noTx, AS-IVT, AS-MT):
- Patients admitted with high suspicion of acute ischemic stroke
- Time of onset of stroke symptoms ≤ 12 hours
- Consent according to the regulations of research in an emergency situation
- Ischemic stroke later confirmed
Exclusion
- All groups:
- Pregnancy
- Age under 18 years
- Acute Stroke no Therapy
- • Acute treatment with IVT or with MT
- Acute Stroke IVT-Group • Acute treatment with MT or without IVT
- Acute Stroke MT-Group
- • Acute treatment without MT
Key Trial Info
Start Date :
February 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2030
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT06530927
Start Date
February 1 2025
End Date
December 1 2030
Last Update
August 29 2025
Active Locations (1)
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1
University Hospital Zurich
Zurich, Canton of Zurich, Switzerland, 8091