Status:

COMPLETED

LncRNA Nicotinamide Nucleotide Transhydrogenase-Antisense RNA1 NNT-AS1 in CRC

Lead Sponsor:

Ain Shams University

Conditions:

Colorectal Cancer

Eligibility:

All Genders

24-76 years

Brief Summary

The current study will compare the blood expression level of lncRNA NNT-AS1 and hsa-miR-485-5p, as well as heat shock protein 90 (HSP90) serum levels in both healthy and CRC Egyptian patients' cohort ...

Detailed Description

Colorectal cancer (CRC) is a heterogeneous malignancy that affects the colon and rectum. It is the third most prevalent and lethal malignancy, with roughly 1.9 million new cases and nearly 9.4% of can...

Eligibility Criteria

Inclusion

  • CRC diagnosed patients that is clinically confirmed by colonoscopy, abdominal radio-imaging, and histopathologicaly.

Exclusion

  • individuals receiving chemotherapy, radiation, or undergone surgery
  • patients with blood disorders
  • patients with any cancer other than CRC.
  • Individuals with inadequate data or missing histopathological diagnoses
  • distant metastases

Key Trial Info

Start Date :

October 1 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 1 2021

Estimated Enrollment :

88 Patients enrolled

Trial Details

Trial ID

NCT06531902

Start Date

October 1 2020

End Date

June 1 2021

Last Update

August 1 2024

Active Locations (1)

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Faculty of Pharmacy, Ain Shams University, Advanced Biochemistry Research Lab

Cairo, Egypt, 11566