Status:
RECRUITING
Gut Microbiota in Chronic GI Diseases
Lead Sponsor:
McMaster University
Conditions:
Microbiota
Eligibility:
All Genders
18-75 years
Brief Summary
The study involves characterizing the microbiota of patients with IBS, functional diarrhea, IBD, severe motility disorders and celiac disease. This will be complemented by a translational phase of hu...
Detailed Description
A complex community of microbes collectively referred to as microbiota, inhabit the human body. The intestinal microbiota is a diverse and dynamic ecosystem, which has developed a mutualistic relation...
Eligibility Criteria
Inclusion
- Diagnosis of IBD, active celiac disease (aTTG positive + endoscopic view and histological findings compatible), IBS (Rome IV criteria or physician diagnosis) severe motility disorders (severe constipation, severe functional dyspepsia) gluten sensitivity (IBS diarrhea predominant with positive anti gliadin antibodies and negative aTTG), functional diarrhea (Rome IV criteria), anal fissure and/or fistula or non-disease control individual or 1st degree family member of celiac patient.
- Willingness to participate
- Signed Informed Consent
Exclusion
- Antibiotics in the last month
- Probiotics in the previous month
Key Trial Info
Start Date :
October 1 2012
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
November 1 2026
Estimated Enrollment :
260 Patients enrolled
Trial Details
Trial ID
NCT06532110
Start Date
October 1 2012
End Date
November 1 2026
Last Update
August 1 2024
Active Locations (1)
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1
McMaster University
Hamilton, Ontario, Canada, L8S 4L8