Status:

RECRUITING

Helmsley 3.0: Abbreviated MRE

Lead Sponsor:

Children's Hospital Medical Center, Cincinnati

Conditions:

Crohn's Disease

Eligibility:

All Genders

10+ years

Brief Summary

The purpose of our study is to compare an abbreviated magnetic resonance imaging (MRI) of the bowel or magnetic resonance enterography (MRE) protocol to a conventional, standard of care MRE in childre...

Detailed Description

This multi-center study will evaluate the effectiveness of an abbreviated magnetic resonance imaging (MRI) of the bowel or magnetic resonance enterography (MRE) to document the presence and severity o...

Eligibility Criteria

Inclusion

  • Established Crohn's disease diagnosis in patients 10 and older
  • Undergoing clinical magnetic resonance enterography (MRE) examinations for any reason(s) below
  • Staging/ restaging/ follow- up of intestinal inflammation
  • Evaluation of known or suspected luminal narrowing/ stricturing disease
  • Evaluation of known or suspected internal penetrating disease

Exclusion

  • Undergoing initial imaging for suspected Crohn's disease where the diagnosis of Crohn's disease has yet to be definitively established
  • New Crohn's disease diagnosis, undergoing baseline imaging
  • Isolated colonic disease
  • Known or suspected pregnancy
  • Contraindication to magnetic resonance imaging (MRI)
  • Ileostomy or prior ileal resection
  • Less than 10 years of age
  • Unable or unwilling to follow imaging procedures
  • Non- English speaking

Key Trial Info

Start Date :

September 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

February 1 2028

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT06533228

Start Date

September 1 2024

End Date

February 1 2028

Last Update

October 27 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Mayo Clinic

Rochester, Minnesota, United States, 55905

2

NYU Langone

New York, New York, United States, 10016