Status:
RECRUITING
Measuring Brain Health Using Low-Field Portable MRI
Lead Sponsor:
Yale University
Collaborating Sponsors:
National Institute of Neurological Disorders and Stroke (NINDS)
Conditions:
White Matter Hyperintensity
Eligibility:
All Genders
50+ years
Brief Summary
The purpose of this study is to develop a new grading scale and utilize automated segmentation for measurement of White Matter Hyperintensity (WMH) volume using a low field MRI.
Detailed Description
This study will take place in one visit, if feasible. This visit will take approximately 2 hours. (Alternatively, the visit can be split over two visits if the subject cannot tolerate two consecutive ...
Eligibility Criteria
Inclusion
- One vascular risk factor, from the following:
- Hypertension (defined as taking an antihypertensive medication)
- Hyperlipidemia (defined as taking a statin or PCSK9 inhibitor)
- Diabetes (defined as taking a medication to prevent hyperglycemia)
Exclusion
- 1\. History of stroke
- History of dementia or other cognitive impairment
- Pacemaker or other MRI contraindications according to the American College of Radiology guidelines
Key Trial Info
Start Date :
February 5 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
November 1 2026
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06533631
Start Date
February 5 2025
End Date
November 1 2026
Last Update
February 11 2025
Active Locations (1)
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1
Yale Magnetic Resonance Research Center (MRRC) at The Analyn Center (TAC)
New Haven, Connecticut, United States, 06520