Status:
COMPLETED
Implication of Genetic Variations in Long Intergenic Non-coding RNA 00511 (LINC00511) in Colorectal Cancer
Lead Sponsor:
Ain Shams University
Collaborating Sponsors:
Academy of Scientific Research and Technology, Egypt
Conditions:
Colorectal Cancer
Eligibility:
All Genders
Brief Summary
As, there is a lack of information about the association between LINC00511 SNP(s) variants and CRC susceptibility, so this study was undertaken to address whether these SNPs would increase CRC risk or...
Detailed Description
1. Introduction 1.1. Background Colorectal cancer (CRC) represents the 7th most common cancer in Egypt. The global burden of CRC is expected to increase 60%, by 2030, in terms of new cases and dea...
Eligibility Criteria
Inclusion
- Adult and confirmed pathological examination of newly diagnosed CRC of no specific type.
Exclusion
- Patients with HBV, schistosomiasis, HIV, alcohol intake, thyroid dysfunction, inflammatory diseases, diabetes mellitus, and cardiovascular disorders.
- Subjects receiving any chemotherapy or radiotherapy, or had undergone a GIT surgical operation, patients with blood disorder diseases, any cancer other than CRC, patients with neuronal diseases, respiratory diseases, uterine diseases, kidney diseases, cirrhosis of the liver, prolonged use of corticosteroids or sex hormones.
Key Trial Info
Start Date :
January 20 2022
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 26 2023
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT06534242
Start Date
January 20 2022
End Date
November 26 2023
Last Update
August 2 2024
Active Locations (1)
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1
Faculty of pharmacy, Ain Shams University, Advanced Biochemisrty Research Lab
Cairo, Egypt