Status:
RECRUITING
Individualized Exercise Combined With Manual Therapy in Severe Hemophilia Patients With Polyarthropathy
Lead Sponsor:
Far Eastern Memorial Hospital
Conditions:
Severe Hemophilia
Eligibility:
All Genders
20+ years
Phase:
NA
Brief Summary
The aim of this study is to investigate the effect of individualized physical therapy, combined manual therapy and exercise intervention, for pain perception, range of motion (ROM), muscle strength, j...
Detailed Description
The main clinical manifestations of hemophilia are muscle and joint bleeding. Recurrent bleeding leads to a degenerative process known as hemophilic arthropathy. Past studies investigated the effect o...
Eligibility Criteria
Inclusion
- over 20 years old and diagnosed with severe hemophilia
- those who receive prophylaxis regularly
- there are more than 2 target joints (hemophilic arthropathy)
Exclusion
- unwilling to sign the informed consent
- any neurological disease or specific musculoskeletal condition (such as fracture) one year ago
- more than 3 (excluding 3) joint replacement surgeries (different joints)
- unable to walk due to hemophilia joint disease or any other diseases
- major bleeding events that pose risks or hinder research
- unable to follow instructions due to cognitive impairment
Key Trial Info
Start Date :
July 5 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT06535971
Start Date
July 5 2024
End Date
December 31 2025
Last Update
March 4 2025
Active Locations (1)
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1
Far Eastern Memorial hospital
New Taipei City, Taiwan, 220