Status:
RECRUITING
New Preclinical and Clinical Approaches to Mesothelioma
Lead Sponsor:
Marco Emilio Bianchi
Collaborating Sponsors:
Istituto Nazionale Tumori IRCCS - Fondazione G. Pascale
Conditions:
Mesothelioma
Eligibility:
All Genders
Brief Summary
This study protocol involves the coordination between UO1 (IRCCS San Raffaele Hospital) and UO2 (Istituto Nazionale Tumori di Napoli - IRCCS G. Pascale) to explore the role of HMGB1 and CXCR4 in cance...
Detailed Description
This is a multicentric cross-sectional observational study with an additional blood volume collected during blood sampling performed for normal clinical practice. The enrollment will take
Eligibility Criteria
Inclusion
- Patients with Mesothelioma:
- Clinical suspicion or histologically confirmed diagnosis of pleural mesothelioma.
- Candidates for surgical intervention.
- Age 18 years or older. It is possible to include both male and female patients, male and female patients of reproductive age, as well as breastfeeding women.
- Capacity to comprehend the study nature and provide autonomously informed consent.
- Control Group patients:
- Absence of pleural mesothelioma but presence of other histologically confirmed diseases (neoplastic, inflammatory, or infectious).
- Candidates for surgical intervention.
- Age 18 years or older. It is possible to include both male and female patients, male and female patients of reproductive age, as well breastfeeding women.
- Ability to understand the study nature and provide autonomously informed consent.
- If the patient's diagnosis, whether provisional or definitive, does not confirm the clinical suspicion, they will not undergo further evaluation in the study.
Exclusion
- Lack of biopsy material.
- pregnancy.
- Unwillingness to sign the Informed Consent.
Key Trial Info
Start Date :
July 25 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 25 2027
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT06536179
Start Date
July 25 2024
End Date
January 25 2027
Last Update
August 2 2024
Active Locations (2)
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1
Istituto Nazionale Tumori IRCCS Fondazione G.Pascale
Napoli, Campania, Italy, 80131
2
IRCCS San Raffaele
Milan, Lombardy, Italy, 20132