Status:

RECRUITING

The Impact of Music Medicine on Preterm Brain Development and Behavior

Lead Sponsor:

Brigham and Women's Hospital

Collaborating Sponsors:

Yale New Haven Health System Center for Healthcare Solutions

Conditions:

Infant Development

Language Development

Eligibility:

All Genders

24-30 years

Phase:

NA

Brief Summary

The investigators are conducting a two-site randomized control trial with the aim of defining the impact of music (M) without or with parent voice (MPV) on very preterm infants' acute and cumulative s...

Detailed Description

Preterm birth remains the leading cause of death for children under five. For survivors, it also accounts for high morbidity and substantial physical, psychosocial, emotional, and financial burden for...

Eligibility Criteria

Inclusion

  • Very preterm infants born between 24+0 and 30+6 weeks' gestational age (GA) from 2 level III NICUs (Brigham and Women's Hospital, Boston, MA and Yale New Haven, CT)
  • Infants who are medically stable per the clinical care team

Exclusion

  • Infants with major genetic or congenital anomalies known to be associated with developmental delay
  • Infants with severe brain injury (such as intraparenchymal hemorrhage, severe white matter injury)
  • Infants who are severely ill infants for whom MBI is not feasible
  • Infants of parents who cannot complete questionnaires in English or Spanish.

Key Trial Info

Start Date :

May 19 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 1 2031

Estimated Enrollment :

243 Patients enrolled

Trial Details

Trial ID

NCT06536296

Start Date

May 19 2025

End Date

March 1 2031

Last Update

June 15 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Yale New Haven Hospital

New Haven, Connecticut, United States, 06510

2

Brigham and Women's Hospital

Boston, Massachusetts, United States, 02115